Table 1.
Baseline characteristics of recipients with periodontitis before kidney transplantation
| Characteristic | Total | Stage I and II | Stage III | Stage IV | p-value |
|---|---|---|---|---|---|
| Patient | 303 (100) | 160 (52.8) | 89 (29.4) | 54 (17.8) | |
| Age (yr) | 43.97 ± 12.28 | 39.04 ± 12.13 | 48.17 ± 10.46 | 51.69 ± 8.50 | <0.001 |
| Male sex | 205 (67.7) | 103 (64.4) | 64 (71.9) | 38 (70.4) | 0.28 |
| Body mass index (kg/m2) | 23.28 ± 3.75 | 22.44 ± 3.70 | 23.74 ± 3.24 | 25.01 ± 4.02 | <0.001 |
| Current smoker | 36 (11.9) | 14 (8.8) | 9 (10.1) | 13 (24.1) | 0.008 |
| Causes of ESKD | |||||
| Diabetes mellitus | 60 (19.8) | 18 (11.3) | 19 (21.3) | 23 (42.6) | <0.001 |
| Hypertension | 75 (24.8) | 30 (18.8) | 31 (34.8) | 14 (25.9) | 0.08 |
| Glomerulonephritis | 85 (28.1) | 62 (38.8) | 16 (18.0) | 7 (13.0) | <0.001 |
| Polycystic kidney disease | 15 (5.0) | 10 (6.3) | 5 (5.6) | 0 (0) | 0.10 |
| Others | 16 (5.3) | 15 (9.4) | 0 (0) | 1 (1.9) | 0.005 |
| Unknown | 52 (17.2) | 25 (15.6) | 18 (20.2) | 9 (16.7) | 0.66 |
| Renal replacement therapy | |||||
| Hemodialysis | 201 (66.3) | 98 (61.3) | 60 (67.4) | 43 (79.6) | 0.02 |
| Peritoneal dialysis | 49 (16.2) | 27 (16.9) | 17 (19.1) | 5 (9.3) | 0.32 |
| Preemptive | 53 (17.5) | 35 (21.9) | 12 (13.5) | 6 (11.1) | 0.04 |
| Dialysis vintage (mo) | 14.94 ± 25.80 | 14.19 ± 22.87 | 17.09 ± 30.33 | 13.53 ± 26.02 | 0.67 |
| Comorbidity | |||||
| Hypertension | 272 (89.8) | 143 (89.4) | 83 (93.3) | 46 (85.2) | 0.20 |
| Diabetes mellitus | 73 (24.1) | 22 (13.8) | 25 (28.1) | 26 (48.1) | <0.001 |
| Dyslipidemia | 185 (61.1) | 93 (58.1) | 54 (60.7) | 38 (70.4) | 0.14 |
| Ejection fraction of heart | 57.26 ± 7.19 | 58.32 ± 6.77 | 56.35 ± 6.76 | 55.54 ± 8.67 | 0.02 |
| Laboratory test | |||||
| Hemoglobin (g/dL) | 10.43 ± 1.68 | 10.44 ± 1.63 | 10.50 ± 1.88 | 10.29 ± 1.51 | 0.76 |
| Albumin (g/dL) | 3.95 ± 0.49 | 4.00 ± 0.48 | 3.90 ± 0.51 | 3.90 ± 0.48 | 0.23 |
| CRP (mg/L), 10 × hsCRPa | 4.88 ± 15.41 | 2.80 ± 5.79 | 5.74 ± 15.07 | 9.68 ± 28.93 | 0.01 |
| LDL (mg/dL) | 85.13 ± 30.47 | 84.70 ± 32.57 | 83.13 ± 28.67 | 89.62 ± 26.88 | 0.46 |
| Triglyceride (mg/dL) | 125.95 ± 85.88 | 124.59 ± 78.57 | 125.51 ± 90.30 | 130.62 ± 99.28 | 0.91 |
| Calcium (mg/dL) ×phosphate (mg/dL) | 47.96 ± 16.42 | 47.24 ± 16.45 | 49.57 ± 16.44 | 47.42 ± 16.42 | 0.55 |
| iPTH (pg/mL) | 250.66 ± 246.75 | 256.21 ± 284.45 | 243.97 ± 208.09 | 245.48 ± 182.61 | 0.92 |
| Donor age (yr) | 45.86 ± 10.92 | 46.21 ± 10.50 | 45.99 ± 11.37 | 44.63 ± 11.52 | 0.65 |
Data are expressed as number (%) or mean ± standard deviation.
CRP, C-reactive protein; ESKD, end-stage kidney disease; hsCRP, high sensitivity CRP; iPTH, intact parathyroid hormone; LDL, low-density lipoprotein.
a
hsCRP of Seoul National University Hospital converted to CRP of Korea University Medical Center with s conversion factor (10) by method of Milone et al. [9].