Table 6.
Risk factors to predict new-onset coronary artery disease
| Variable | Crude model |
Multivariate model |
||
|---|---|---|---|---|
| OR (95% CI) | p-value | OR (95% CI) | p-value | |
| Female sex | 0.31 (0.04–2.59) | 0.28 | ||
| Age (yr) | 1.02 (1.00–1.17) | 0.04 | ||
| Year of KT | 1.13 (0.74–1.71) | 0.58 | ||
| HbA1c (% of THb) | 1.35 90.83–2.18) | 0.23 | ||
| Donor age (yr) | 0.95 (0.89–1.01) | 0.09 | ||
| Ca (mg/dL) | 1.54 (0.66–3.59) | 0.32 | ||
| iPTH (pg/mL) | 0.997 (0.99–1.00) | 0.24 | ||
| Body mass index | 1.09 (0.90–1.32) | 0.37 | ||
| Dyslipidemia | 1.49 (0.36–6.12) | 0.58 | ||
| Causes of ESKD | ||||
| Diabetes mellitus | 7.07 (1.62–30.93) | 0.009 | 4.73 (1.08–20.77) | 0.04 |
| Glomerulonephritis | 0.26 (0.03–2.15) | 0.21 | ||
| Periodontitis stage | ||||
| Stage I and II | 1.00 | |||
| Stage III | 1.65 (0.27–10.20) | 0.59 | ||
| Stage IV | 6.20 (1.17–32.89) | 0.03 | ||
CI, confidence interval; ESKD, end-stage kidney disease; iPTH, intact parathyroid hormone; KT, kidney transplantation; OR, odds ratio.
In the multivariate logistic analysis model, age, male sex, donor age, hemoglobin A1c, iPTH, cause of end-stage renal disease (diabetes mellitus, glomerulonephritis), year of KT, stage of periodontitis were adjusted. Multivariate logistic regression was performed with variables with p-value less than 0.3 in univariate analysis; a backward stepwise selection approach was adopted. All laboratory data were examined prior to KT. Dyslipidemia was defined as those with low-density lipoprotein cholesterol greater than 100 mg/dL or triglyceride greater than 500 mg/dL or under lipid-lowering agent.