Table 1.
S. No | Formulation code | ZD (g) | Polymer content (g) | Eudragit S 100 (g) | |
---|---|---|---|---|---|
PVP | HPMC | ||||
1 | SDZDPS | 1.0 | 7.2 | - | 1.8 |
2 | SDZDHS | 1.0 | - | 7.2 | 1.8 |
3 | SDZDHS-M | 1.0 | - | 7.1 | 1.9 |
4 | SDZDHS-Z | 1.0 | - | 7.0 | 2.0 |
*The formulated solid dispersions codes were constructed in a manner to better elucidate their constituents. For example, in ‘SDZDPS’ or ‘SDZDHS’, SD represents solid dispersions, while (ZDPS or ZDHS) represents solid dispersion constituents of gefitinib (ZD), PVP, Eudragit S 100 for ZDPS; and gefitinib (ZD), HPMC, Eudragit S 100 for ZDHS
**M or Z indicates the polymer content for HPMC and Eudragit S 100 in the dispersions (as shown in the above table)