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. 2022 Jan 5;24(1):22. doi: 10.1208/s12248-021-00668-9

Table IV.

Results of Kinetic Solubility Measurements

Type of additive Additive Additive concentration (μg/mL) Kinetic solubility (μg/mL) SD t-test (p value)
- 0 37.27 3.17 -
Surfactants/complexing agents SDS 850 45.87 4.80 0.02
Tween 80 0.45 64.27 7.30 0.01
HPβCD 1386 37.50 0.75 0.88
Polymers HMPC 2910 212 30.90 0.96 0.05
PVP K90 212 34.37 1.15 0.36
PVP K30 212 34.70 1.18 0.41
HPMC-AS 212 34.10 2.70 0.20
Fillers Sorbitol 667 30.73 1.76 0.03
Mannitol 667 39.67 0.31 0.31
Lactose monohydrate 667 32.80 2.42 0.25