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. 2022 Jan 5;24(1):22. doi: 10.1208/s12248-021-00668-9

Table VII.

Permeability Data of Large-Scale Dissolution-Permeation Assay of TEL Containing Final Dosage Forms

Formulation Pe (10−4 cm/sec) SD t-test compared to amorphous (p value) t-test compared to Micardis (p value)
Micardis 1.16 0.06 0.01
Tel_amorphous 1.03 0.03 0.01
Tel_Na_PVP_sorbitol 1.16 0.08 0.05 0.97
Tel_Na_PVP_mannitol 1.13 0.03 0.02 0.42
Tel_Na_HPMC-AS_sorbitol 1.15 0.07 0.04 0.93
Tel_Na_HPMC-AS_mannitol 1.07 0.05 0.21 0.09