Figure 2.

Shift in the cecal microbiome of high-fat/high-sucrose (HF/HS) male and female offspring. A: Bray–Curtis plots for β-diversity of cecal microbiome from HF/HS and chow (CON) offspring. B: measures of α-diversity (observed OTUs, Faith PD, and Shannon diversity) in cecal microbiome of HF/HS and CON offspring. C: relative abundance of each bacterial family in cecal microbiome of HF/HS and CON offspring. D: ratio of Firmicutes to Bacteroidetes in cecal microbiome of HF/HS and CON offspring. Quantitative data presented as means ± SE with n = 10 in each group and ≥5 separate litters represented in each group. Male and female offspring included in each section. P values as indicated on graph for t tests. OTU, operational taxonomic unit; PD, phylogenetic diversity.