Figure 2.

Sarcolipin ablation ameliorates glucose homeostasis in mdx mice. A: fasting blood glucose levels in WT, mdx, mdx:sln^+/−, and mdx:sln^−/− mice. Glucose clearance rate measured by intraperitoneal glucose tolerance test (ipGTT) and area under the curve (AUC; B) and insulin tolerance test (ITT) and AUC (C) in WT, mdx, mdx:sln^+/−, and mdx:sln^−/− mice. Data represent means ± SD. n = 8 mice/group. *P < 0.05 vs. other groups. Male and female mice were used in equal numbers in each experiment. WT, wild type.