Table 1.
Characteristics | ARDS Berlin definition |
---|---|
Timing | Within 7 days of a known clinical insult or new or worsening respiratory symptoms |
Oxygenation | Mild: PaO2/FiO2 >200 mmHg, but ≤300 mmHg; |
Moderate: PaO2 /FiO2 >100 mmHg, but ≤200 mmHg; | |
Severe: PaO2 /FiO2 ≤100 mmHg | |
PEEP requirement | Minimum 5 cm H2O PEEP required by invasive mechanical ventilation |
Chest imaging | Bilateral opacities not fully explained by effusions, lobar/lung collapse or nodules by chest radiograph or CT |
Origin of edema | Respiratory failure not fully explained by cardiac failure or fluid overload (need objective assessment, such as echocardiography, to exclude hydrostatic edema if no risk factor present) |
PEEP: positive end-expiratory pressure; PaO 2 : arterial oxygen tension; FiO 2 : inspiratory oxygen fraction; CT: computed to-mography.