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. 2022 Feb 5;21:100202. doi: 10.1016/j.mran.2022.100202

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Fig. 1. — Evolution of Gibbs energy of binding and susceptibility coefficient of SARS-CoV-2. (a) The SARS-CoV-2 mutant strains are characterized by a more negative Gibbs energy of binding compared to the wild type. (b) The susceptibility coefficient has been increasing with new mutations on the SARS-CoV-2 virus.