Table 2:
Lymphodepletion* (number [%]) | |
Flu (120 mg/m2)/Cy (1000 mg/m2) | 19 (61.3) |
Flu (75 mg/m2)/Cy (900 mg/m2) | 10 (32.3) |
Flu (75 mg/m2)/Cy (900 mg/m2)/Eto (500 mg/m2) | 1 (3.2) |
Flu (75 mg/m2)/Cy (900 mg/m2)/Ara-C (4 g/m2) | 1 (3.2) |
| |
CAR T-cell dose administered (median [range]) | |
Patients ≤ 50 kg (n = 21) | 2.1 [0.9–4.5] ** |
Patients > 50 kg (n = 10) | 1.1 [0.5–1.6] *** |
Flu: fludarabine; Cy: cyclophosphamide; Eto: etoposide; Ara-C: cytarabine
cumulative doses
×106 CAR-positive T cells/kg patient weight
×108 CAR-positive T cells.