Fig. 1.

HOXB8 expression is upregulated in ovarian cancer tissues and cells. A The mRNA level of HOXB8 in 55 paired ovarian cancer tissues and matched adjacent normal ovarian tissues were measured by qRT-PCR. B The HOXB8 level was detected by staining with IHC (scale bar = 200 μm, magnification, ×100). C, D The mRNA (F) and protein (G) levels of HOXB8 in in ovarian cancer cell lines (CAOV3, SKOV3, OVCAR4, A2780, TOV-21G) and the normal ovarian epithelial cell line HOSEpiC were determined by qRT-PCR and western blot assays. Data are shown as mean ± SD; *P < 0.05, **P < 0.01 and ***P < 0.001