Fig. 5.

Knockdown of HOXB8 inhibits the growth of ovarian cancer xenograft tumors in vivo. A Photographs of tumors excised from the mice injected with SKOV3 cells transfected with shNC or shHOXB8. B, C Tumor growth curves (B) and weight (C) of mice injected with SKOV3 cells. (D)The levels of HOXB8, Ki-67 and E-cadherin in tumors from mice injected with SKOV3 cells were evaluated by IHC staining (scale bar = 200 μm, magnification, ×100). Data are shown as mean ± SD; *P < 0.05, **P < 0.01 and ***P < 0.001