TABLE 2.

Outcome data for 24 patients with candidemia

Patient no.	Candida sp.	Therapy	Daily dose (mg)	Duration of therapy (days)	Clinical outcome	Microbiological outcome	Fluconazole MIC (μg/ml) by:		Amphotericin B MIC (μg/ml) by:
							NCCLS M27-A	FACS assay	NCCLS M27-A	FACS assay
1	C. albicans	Fluconazole	400	25	Cure	Eradication	0.5	0.5	0.125	0.06
2	C. glabrata	Fluconazole	600	14	Death	Persistence	64	128	0.125	0.06
3	C. glabrata	Amphotericin	50	14	Cure	Eradication	16	8	0.06	0.03
4	C. albicans	Fluconazole	1,200	28	Death	Eradication	0.5	1	0.125	0.125
5	C. albicans	Fluconazole	1,000	28	Cure	Eradication	0.25	0.25	0.125	0.25
6	C. albicans	Fluconazole	600	3	Death	Persistence	1	2	0.125	0.125
7	C. albicans	Fluconazole	400	21	Cure	Eradication	0.25	0.25	0.125	0.25
8	C. albicans	Fluconazole	400	12	Death	NAa	0.5	2	0.125	0.125
9	C. pelliculosa	Fluconazole	600	14	Cure	Eradication	4	4	0.03	0.06
10	C. humicola	Fluconazole	800	10	Death	Persistence	>128	>128	0.03	0.03
11	C. albicans	Fluconazole	400	14	Death	NA	0.5	8	0.06	0.06
12	C. albicans	Amphotericin	50	24	Death	Persistence	32	64	0.25	0.125
13	C. albicans	Fluconazole	400	10	Death	Persistence	0.5	4	0.125	0.25
14	C. albicans	Fluconazole	400	14	Cure	Eradication	0.5	0.25	0.06	0.03
15	C. albicans	Fluconazole	12	10	Cure	Eradication	0.5	0.5	0.125	0.125
16	C. albicans	Fluconazole	400	16	Cure	Eradication	0.5	0.25	0.125	0.03
17	C. albicans	Amphotericin	60	12	Cure	Eradication	0.25	0.5	0.125	0.03
18	C. albicans	Fluconazole	600	21	Cure	Eradication	0.5	0.25	0.125	0.125
19	C. albicans	Fluconazole	600	14	Cure	NA	1	0.5	0.125	0.125
20	C. albicans	Fluconazole	800	18	Death	Persistence	0.5	8	0.125	0.25
21	C. albicans	Fluconazole	400	24	Cure	Eradiaction	1	0.5	0.125	0.25
22	C. albicans	Fluconazole	400	14	Cure	Eradication	0.5	0.5	0.125	0.125
23	C. albicans	Fluconazole	600	14	Cure	Eradication	0.5	0.5	0.125	0.125
24	C. albicans	Fluconazole	200	14	Cure	Eradication	2	1	0.125	0.25

^aNA, not applicable.