Table 3.
Logistic regression model for mortality at the end of follow-up
| OR (95% CI) | |||
|---|---|---|---|
| Parameter | Model 1 | Model 2 | Model 3 |
| OUD (vs. non-OUD) | 1.44 (1.20–1.73)*** | 1.49 (1.22–1.81)*** | 1.42 (1.13–1.77)** |
| BDZ prescription in the last month (vs. none) | 2.58 (2.11–3.14)*** | 2.80 (2.26–3.48)*** | |
| Opioid prescription in the last month (vs. none) | 1.73 (1.43–2.10)*** | 1.68 (1.37–2.06)*** | |
| 10 DME per day in the last month | 1.34 (1.15–1.55)*** | ||
| 10 MME per day in the last month | 1.04 (1.02–1.05)*** | ||
| Socio-demographics | |||
| Age at the end of follow-up (years) | 1.05 (1.04–1.06)*** | 1.02 (1.01–1.03)*** | |
| Female (vs. male) | 0.66 (0.54–0.81)*** | 0.85 (0.67–1.06) | |
| White (vs. non-white) | 1.00 (0.81–1.24) | 0.92 (0.73–1.15) | |
| Self-pay/other (vs. public and private insurance) | 6.71 (5.35–8.41)*** | 8.61 (6.72–11.02)*** | |
| Substance use disorders | |||
| Alcohol | 1.47 (1.16–1.86)** | ||
| Amphetamine | 0.65 (0.42–1.01) | ||
| Cocaine | 0.72 (0.49–1.06) | ||
| Marijuana | 1.26 (0.88–1.80) | ||
| Tobacco | 0.96 (0.72–1.28) | ||
| Comorbidity | |||
| Heart | 2.69 (2.07–3.49)*** | ||
| Liver | 3.07 (2.38–3.95)*** | ||
| Cancer | 2.07 (1.60–2.67)*** | ||
| Chronic pain | 1.08 (0.85–1.36) | ||
| HIV | 1.44 (0.70–2.96) | ||
| HCV | 1.55 (1.18–2.04)** | ||
| Any mental disorders | 1.15 (0.92–1.45) | ||
| AIC | 3345.06 | 2883.19 | 2598.18 |
| −2 Log-likelihood | 3337.06 | 2867.19 | 2558.18 |
Note: OUD, opioid use disorder; BDZ, benzodiazepine; DME, diazepam milligram equivalents; MME, morphine milligram equivalent.
*
p<0.05,
**
p<0.01,
***
p<0.001