TABLE 2.

Candidate targets of miR‐155 and miR‐200 in gastric diffuse large B‐cell lymphomas resistant (R) or sensitive (S) to H. pylori eradication therapy

Candidate targets of miR‐155					Candidate targets of miR‐200
Gene	R	S	R/S	p	Gene	S	R	S/R	p
DEPTOR	555	1613	0.34	0.005	LGALS9C	35,845	13,308	2.69	0.0004
EGLN3	651	818	0.8	0.016	LGALS9	3237	1501	2.15	0.006
SCNN1A	283	835	0.34	0.019	SAMD12	426	169	2.5	0.008
FCGR2A	3263	474	6.88	0.036	SELL	303	2676	0.11	0.04
ACVR1C	142	175	0.81	0.12	CXCL10	289	1414	0.2	0.09
COPZ2	156	129	1.21	0.13	CXCL9	1656	6578	0.25	0.09
DPP9	662	519	1.28	0.13	IFITM3	12,370	28,154	0.44	0.10
KRTAP5‐3	62	53	1.16	0.15	CCL4	1929	3818	0.51	0.12
KIF26A	67	52	1.29	0.23	IFITM1	2226	4952	0.45	0.12
F8	1203	1433	0.84	0.27	REXO1L1	67	91	0.74	0.12
NUDT10	1377	1486	0.93	0.27	AICDA	38	585	0.064	0.15
TAS2R20	8	14	0.62	0.27	C1QB	2891	6444	0.45	0.16
AQP6	109	126	0.87	0.32	TMPRSS4	853	633	1.34	0.19
GRK1	195	220	0.89	0.37	AIRE	1061	900	1.18	0.22
WDR7	717	584	1.23	0.38	PTGS1	292	219	1.33	0.23
ICA1L	17	21	0.83	0.43	AIM2	1335	2990	0.45	0.28
CYP21A2	1042	1099	0.95	0.65	ZNF431	10	15	0.72	0.28
PIGK	260	236	1.1	0.68	CCDC24	42	58	0.72	0.29
ABI3BP	567	597	0.95	0.75	CEBPA	446	350	1.28	0.3
RBPMS	526	546	0.96	0.82	GTF2IRD2B	266	208	1.28	0.36
KCNC1	69	72	0.96	0.89	CACNA1B	1175	1105	1.06	0.45
					LY6E	522	642	0.81	0.53
					NRXN2	184	194	0.94	0.72
					ST3GAL4	357	447	0.8	0.72
					EME2	177	183	0.97	0.76
					SLCO4A1	233	215	1.08	0.85
					COL27A1	3849	3915	0.98	0.86
					STRA8	8.6	8.4	1.02	0.91
					IFI44L	620	602	1.03	0.92
					B3GNT7	492	345	1.42	1.43

Transfection of miR‐155 into BJAB cells identified 22 suppressed transcripts (Table S1). Levels of the candidate targets in biopsy specimens of gastric DLBCLs are listed here. Only DEPTOR was significantly reduced in HPET‐resistant gastric DLBCLs.

Transfection of miR‐200 into U2932 cells identified 30 suppressed transcripts. (Table S2). Levels of the candidate targets in biopsy specimens of gastric DLBCLs are listed here. Only SELL was significantly reduced in HPET‐sensitive gastric DLBCLs.

Abbreviations: DLBCL, diffuse large B‐cell lymphoma; HPET, H. pylori eradication therapy.