FIGURE 3.

Identification of the lncRNA signature derived from genomic instability for predicting the LUAD patients' clinical outcomes. (A) Estimates of the LUAD patients' overall survival (OS) in the training set using the Kaplan‐Meier method. All 246 LUAD patients in this set were assigned into the high‐risk or the low‐risk group. Univariate Cox analysis and the log‐rank test were carried out to do the statistical analysis. (B) Analysis of the 3‐year time‐dependent ROC curves for the signature in the training set. (C) LncRNA expression patterns, somatic mutation number's distribution and the UBQLN4 expression's distribution along with the increase of the GILncSig scores. (D) Distribution of somatic mutations for LUAD patients in two risk groups. (E) Expression of UBQLN4 in both groups with different risks. Median values were reflected by horizontal lines. The Mann‐Whitney U test was carried out to analyze those statistics