TABLE 4.
Cox regression analyses for OS
| Clinicopathological characteristics | Hazard ratio (95%CI) | p values |
|---|---|---|
| Gender | ||
| Female | Reference | |
| Male | 1.374(1.236–1.527) | <0.001 |
| Age | ||
| <=60 | Reference | |
| 60–70 | 1.384(1.337–1.433) | <0.001 |
| >70 | 3.001(2.910–3.094) | <0.001 |
| Race | ||
| White | Reference | |
| Black | 1.195(1.153–1.239) | <0.001 |
| Others | 0.766(0.734–0.800) | <0.001 |
| Laterality | ||
| Right | Reference | |
| Left | 0.992(0.969–1.016) | 0.513 |
| Other | 0.881(0.766–1.014) | 0.078 |
| Marital status | ||
| Married | Reference | |
| Unmarried | 1.401(1.365–1.438) | <0.001 |
| Unknown | 1.187(1.126–1.251) | <0.001 |
| Histology | ||
| Ductal | Reference | |
| Lobular | 1.027(0.986–1.070) | 0.2 |
| Other | 1.045(1.008–1.083) | 0.016 |
| Grade | ||
| Ⅰ | Reference | |
| Ⅱ | 1.169(1.125–1.215) | <0.001 |
| Ⅲ/Ⅳ | 1.714(1.644–1.788) | <0.001 |
| Unknown | 1.293(1.221–1.369) | <0.001 |
| AJCC T classification | ||
| T1 | Reference | |
| T2 | 1.607(1.557–1.658) | <0.001 |
| T3 | 2.189(2.091–2.293) | <0.001 |
| T4 | 2.598(2.476–2.725) | <0.001 |
| Other | 1.643(1.547–1.744) | <0.001 |
| AJCC N classification | ||
| N0 | Reference | |
| N1 | 1.346(1.304–1.389) | <0.001 |
| N2 | 1.955(1.865–2.049) | <0.001 |
| N3 | 2.345(2.233–2.463) | <0.001 |
| Unknown | 1.555(1.459–1.657) | <0.001 |
| AJCC M classification | ||
| M0 | Reference | |
| M1 | 2.489(2.395–2.588) | <0.001 |
| Unknown | 0.694(0.616–0.782) | <0.001 |
| Molecular subtype | ||
| HoR−/HER2− | Reference | |
| HoR−/HER2+ | 0.565(0.0.533–0.598) | <0.001 |
| HoR+/HER2− | 0.486(0.469–0.504) | <0.001 |
| HoR+/HER2+ | 0.454(0.433–0.476) | <0.001 |
| Surgery | ||
| Yes | Reference | |
| No/unknown | 0.337(0.325–0.349) | <0.001 |
| Chemotherapy | ||
| Yes | Reference | |
| No/unknown | 0.667(0.649–0.685) | <0.001 |
| Radiation therapy | ||
| Yes | Reference | |
| No/unknown | 0.725(0.703–0.747) | <0.001 |