FIGURE 8.

Uridine alleviates oxidative stress caused by CCl4. (A) Uridine pre‐treatment decreased ROS level. (B) Confocal microscopic analysis of ROS level. (C) The effect of uridine on the content of SOD activity, GSH‐Px and GSH. The oxidative stress model was established by 24 h treatment with CCl4 (10 mmoL/L). The cells were pre‐treated with uridine (0.2–0.4 mg/ml) for 10 h before CCL4 stimulation, after which cell samples were collected and subjected to ELISA kit according to manufacturer's instructions. Asterisks indicate significant differences between means (p < 0.05)