Fig. 4.

Effect of changing the cell size on lycopene production. a Specific lycopene yield and biomass of E. coli when genes affecting cell size were deleted. The lycopene pathway comprising module 1, 2 and 3 (Table 2) are overexpressed in each of single-deleted cells. All the measurements were average of triplicates with standard error bar shown in the figure. b Flow cytometry analysis on cell size distribution of single-deleted genotype. c Microscopy image of wildtype and zapB null strain with and without lycopene production. d Size distribution of wildtype and zapB null strain with and without lycopene production. They were obtained by imageJ analysis