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. 2022 Feb 4;22:35. doi: 10.1186/s12906-021-03488-8

Table 7.

Water Solubility (Log S) values of the three predictors for curcumin, trans-resveratrol, quercetin and (1 s,4 s)-eucalyptol. The water solubility is provided in mg/ml and mol/l along with qualitative solubility classes

Curcumin Trans-resveratrol Quercetin (1 s,4 s)-Eucalyptol
Log S (ESOL) −3.94 −3.62 − 3.16 − 2.52
Solubility

4.22e-02 mg/ml

1.15e-04 mol/l

5.51e-02 mg/ml

2.41e-04 mol/l

2.11e-01 mg/ml 6.98e-04 mol/l 4.63e-01 mg/ml 3.00e-03 mol/l
Class Soluble Soluble Soluble Soluble
Log S (Ali) −4.83 − 4.07 −3.91 − 2.59
Solubility

5.50e-03 mg/ml

1.49e-05 mol/l

1.93e-02 mg/ml

8.44e-05 mol/l

3.74e-02 mg/ml 1.24e-04 mol/l 3.98e-01 mg/ml 2.58e-03 mol/l
Class Moderately soluble Moderately soluble Soluble Soluble
Log S (SILICOS-IT) −4.45 −3.29 − 3.24 − 2.45
Solubility

1.31e-02 mg/ml

3.56e-05 mol/l

1.18e-01 mg/ml

5.16e-04 mol/l

1.73e-01 mg/ml 5.73e-04 mol/l 5.45e-01 mg/ml 3.53e-03 mol/l
Class Moderately soluble Soluble Soluble Soluble