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. 2022 Feb 4;22:35. doi: 10.1186/s12906-021-03488-8

Table 9.

Prediction of the drug likeness for curcumin, trans-resveratrol, quercetin and (1 s,4 s)-eucalyptol. Five rule-based filters and the bioavailability score were used

Curcumin Trans-resveratrol Quercetin (1 s,4 s)-Eucalyptol
Lipinski rule Yes; 0 violation Yes; 0 violation Yes; 0 violation Yes; 0 violation
Ghose rule Yes Yes Yes No; 1 violation: MW < 160
Veber rule Yes Yes Yes Yes
Egan rule Yes Yes Yes Yes
Muegge rule Yes Yes Yes No; 2 violations: MW < 200, Heteroatoms< 2
Bioavailability Score 0.55 0.55 0.55 0.55