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. 2022 Feb 5;21:33. doi: 10.1186/s12936-022-04054-4

Table 1.

The plasma pharmacokinetic parameters of SPQ and RPQ in mice

SPQ RPQ
Lag time (h) 0 0
Cmax (µg/mL) 1.05 ± 0.15 0.72 ± 0.11
Tmax (h) 1 0.5
Tlast (h) 8 2
AUC0-last (µg h/mL) 1.58 0.64
T1/2 (h) 1.9 0.45

Cmax maximum plasma concentration, Tmax time for Cmax, Tlast time for last measurable plasma concentration, AUC area under the plasma concentration–time curve, T1/2 half-life