Table 1.

Elderly glioblastoma patient trials

Study	Age	Patients	Treatment	Dosing regimen	Median OS (months)
Nordic Malmstrom et al. [20]	≥ 60	291	TMZ	5/28 days	8.3
			hRT	34 Gy	7.5
			RT	60 Gy	6.0
	> 70	123	TMZ	5/28 days	9.0
			RT	34 Gy	7.0
			RT	60 Gy	5.2
NOA-08 Wick et al. [19]	> 65	373	RT	60 Gy	9.6
			TMZ	7 days on, 7 days off	8.6
CCTG/EORTC 26062 Perry et al. [64]	> 65	562	RT+TMZ	60 Gy	5.3
			RT+TMZ	40 Gy	9.3
ANOCEF trial Keime-Guibert et al. [50]	≥ 70	85	RT	50 Gy	6.7
			Supportive care		3.9

NOA Neurooncology Working Group; Canadian Cancer Trials Group (CCTG); EORTC European Organisation for Research and Treatment of Cancer (EORTC); ANOCEF The Association des Neuro-Oncologues d’Expression Française; TMZ temozolomide; hRT hypofractionated radiation therapy