Table 1.
Detailed Computation of Nucleus Volumes from a Previous Histology Atlas (Paxinos et al., 2012) and from the Current Study
| Nucleus name (acronym) | Prior study (Paxinos et al., 2012) |
Current study |
|||
|---|---|---|---|---|---|
| Subnucleus name (acronym) | Volume (mm3) | Total volume (mm3) | Right nucleus volume (mm3) mean ± SE | Left nucleus volume (mm3) mean ± SE | |
| Mesencephalic reticular formation (mRt) | Mesencephalic reticular formation (mRt) | 237.28 | 389.13 | 373.46 ± 16.55 | 369.46 ± 16.83 |
| P1 reticular formation (p1RT) | 141.66 | ||||
| Central mesencephalic nucleus (CeMe) | 5.49 | ||||
| Retroparafascicular nucleus (RPF) | 4.70 | ||||
| Isthmic reticular formation (isRt) | Isthmic reticular formation (isRT) | 48.74 | 58.48 | 57.79 ± 2.42 | 53.91 ± 3.30 |
| Nucleus U (U) | 9.75 | ||||
| Microcellular tegmental nucleus–prabigeminal nucleus (MiTg-PBG) | Microcellular tegmental nucleus–spinothalamic tract (MiTg-spth) | 22.11 | 27.86 | 28.06 ± 1.22 | 26.18 ± 1.01 |
| Prabigeminal nucleus (PBG) | 5.75 | ||||
| Ventral tegmental area–parabrachial pigmented nucleus complex (VTA-PBP) | Parabrachial pigmented nucleus of the ventral tegmental area (PBP) | 117.60 | 267.88 | 274.63 ± 6.73 | 276.07 ± 5.87 |
| Ventral tegmental area (VTA) | 99.09 | ||||
| Interpeduncular nucleus, caudal subnucleus (IPC) | 20.95 | ||||
| Interpeduncular fossa (PIF) | 14.21 | ||||
| Parapeduncular nucleus (PaP) | 7.55 | ||||
| Paranigral nucleus of the ventral tegmental | 6.63 | ||||
| area (PN) | |||||
| Interpeduncular nucleus, dorsomedial | 1.22 | ||||
| subnucleus (IPDM) | |||||
| Interfascicular nucleus (IF) | 0.63 | ||||
| Caudal–rostral linear nucleus of the raphe (CLi-RLi) | Rostral linear nucleus (RLi) | 62.04 | 107.75 | 110.69 ± 3.59 | |
| Caudal linear nucleus of the raphe, zygoz | 31.90 | ||||
| part (CLiZ) | |||||
| Caudal linear nucleus of the raphe, azygoz | 13.81 | ||||
| part (CLiAz) | |||||
Statistical analysis: volumes of left nuclei did not significantly differ from volumes of right nuclei (paired one-sample t-test, p < 0.05, computed on mRt, isRt, MiTg-PBG, and VTA-PBP); the volumes of our labels did not differ from Paxinos' volumes (p < 0.05) (Paxinos et al., 2012).
isRt, isthmic reticular formation; MiTg-PBG, microcellular tegmental nucleus–prabigeminal nucleus; mRt, mesencephalic reticular formation; SE, standard error; VTA-PBP, ventral tegmental area–parabrachial pigmented nucleus complex.