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. 2021 Oct 14;11(8):624–638. doi: 10.1089/brain.2020.0841

Table 1.

List of Free Model Parameters and Their Nominal Values

Parameter name Symbol Nominal value (a.u.)
Oligomeric τ of size m τm  
Seed region vseed vEC(entorhinal)
Time scale of monomer production function fτt σf 25
Network diffusivity/transmission rate for oligomer of size m dm  
Scaling constant that governs the relationship between dm and oligomer size m σdiff 1
Global network “transmissibility” constant, governing relative propensity to aggregate in situ versus spread over network β 1
Global constant relating aggregation rate to network diffusivity c 1 1
Global constant relating monomer production rate to network diffusivity c 2 0.05
Reaction kinetic rates for the aggregation of two polymers of lengths jandk aj,k  
Scaling constant that governs the relationship between aj,k and oligomer sizes j,k σagg 2

Some variables are shown for context (shaded) but they are not free parameters themselves.