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. Author manuscript; available in PMC: 2022 May 1.
Published in final edited form as: Hum Pathol. 2021 Jan 30;111:36–44. doi: 10.1016/j.humpath.2021.01.003

Figure 1:

Figure 1:

Normal colonic mucosa exhibits cytoplasmic expression of Das-1 (A), while normal small intestinal mucosa is negative for Das-1 (B). Similarly, normal pancreatic parenchyma including pancreatic ducts are non-reactive to Das-1 (C: H&E stain, D: Das-1 immunohistochemistry). Interestingly, rare small foci with acinar to ductal metaplasia in the setting of chronic pancreatitis secondary to pancreatic ductal adenocarcinoma shows strong membranous and/or cytoplasmic Das-1 expression (E: H&E stain, F: Das-1 immunohistochemistry).