(a) Top enriched pathways in the shared DEmiRNA-gene network
| KEGG pathway | p value |
| Glioma | 4.48E-06 |
| Neurotrophin signaling pathway | 4.51E-06 |
| Prostate cancer | 3.14E-05 |
| Pathways in cancer | 7.11E-05 |
| Melanoma | 7.23E-05 |
| Chronic myeloid leukemia | 0.000108 |
| Bladder cancer | 0.000225 |
| Cell cycle | 3.00E-04 |
| Cysteine and methionine metabolism | 0.000422 |
| p53 signaling pathway | 0.000713 |
| Reactome pathway | |
| Signaling by SCF-KIT | 1.43E-05 |
| Oncogene induced senescence | 1.70E-05 |
| Pre-NOTCH transcription and translation | 4.81E-05 |
| PI3K events in ERBB4 signaling | 7.45E-05 |
| PIP3 activates AKT signaling | 7.45E-05 |
| PI3K events in ERBB2 signaling | 7.45E-05 |
| PI-3K cascade:FGFR1 | 7.45E-05 |
| PI-3K cascade:FGFR2 | 7.45E-05 |
| PI-3K cascade:FGFR3 | 7.45E-05 |
| PI-3K cascade:FGFR4 | 7.45E-05 |
| GO-BP | |
| Negative regulation of metabolic process | 1.46E-09 |
| Negative regulation of cellular metabolic process | 1.96E-09 |
| Negative regulation of transcription from RNA polymerase II promoter | 2.02E-09 |
| Negative regulation of cellular biosynthetic process | 5.27E-09 |
| Negative regulation of biosynthetic process | 7.61E-09 |
| Negative regulation of transcription, DNA-dependent | 9.74E-08 |
| Negative regulation of transcription, DNA-dependent | 9.74E-08 |
| Negative regulation of RNA metabolic process | 1.93E-07 |
| Negative regulation of nucleobase-containing compound metabolic process | 3.08E-07 |
| Generation of neurons | 1.23E-06 |
| GO-MF | |
| Protein kinase binding | 4.93E-09 |
| Kinase binding | 2.20E-08 |
| Negative regulation of transcription, DNA-dependent | 3.35E-08 |
| Chromatin binding | 4.92E-07 |
| Transcription factor binding | 1.78E-06 |
| Enzyme binding | 4.41E-06 |
| Transcription from RNA polymerase II promoter | 8.05E-06 |
| Transcription corepressor activity | 8.85E-05 |
| SMAD binding | 1.00E-04 |
| Protein binding transcription factor activity | 0.000788 |
| GO-CC | |
| Cytosol | 4.70E-07 |
| Nucleoplasm | 2.96E-06 |
| Nuclear lumen | 5.22E-06 |
| Organelle lumen | 8.75E-06 |
| Nucleoplasm part | 9.20E-06 |
| Macromolecular complex | 1.19E-05 |
| Membrane-enclosed lumen | 1.35E-05 |
| Transcription factor complex | 1.65E-05 |
| Membrane-bounded vesicle | 3.32E-05 |
| Nuclear chromatin | 5.44E-05 |