(b) Top enriched pathways in shared DEmiRNA-TF network
| KEGG pathway | p value |
| Acute myeloid leukemia | 2.72E-08 |
| Pathways in cancer | 5.71E-06 |
| Chronic myeloid leukemia | 0.000286 |
| Epstein-Barr virus infection | 0.000549 |
| Transcriptional misregulation in cancer | 0.000553 |
| Adipocytokine signaling pathway | 0.00604 |
| Pancreatic cancer | 0.00721 |
| Small cell lung cancer | 0.00961 |
| Toxoplasmosis | 0.0128 |
| Jak-STAT signaling pathway | 0.0145 |
| Reactome pathway | |
| Cellular responses to stress | 6.47E-05 |
| Cellular senescence | 0.000306 |
| NOTCH1 intracellular domain regulates transcription | 0.000706 |
| Transcriptional regulation of white adipocyte differentiation | 0.00143 |
| Signaling by NOTCH1 | 0.00159 |
| Senescence-associated secretory phenotype (SASP) | 0.00228 |
| Signaling by NOTCH | 0.00323 |
| DEx/H-box helicases activate type I IFN and inflammatory cytokines production | 0.00724 |
| Binding of TCF/LEF:CTNNB1 to target gene promoters | 0.00724 |
| IkBA variant leads to EDA-ID | 0.00724 |
| GO-BP | |
| Regulation of cell differentiation | 3.46E-11 |
| Regulation of developmental process | 1.51E-09 |
| Cell proliferation | 1.72E-09 |
| Transcription from RNA polymerase II promoter | 1.97E-09 |
| Positive regulation of transcription from RNA polymerase II promoter | 3.80E-09 |
| Regulation of multicellular organismal process | 2.44E-08 |
| Regulation of transcription from RNA polymerase II promoter | 2.55E-08 |
| Positive regulation of transcription, DNA-dependent | 1.35E-07 |
| Positive regulation of transcription, DNA-dependent | 1.35E-07 |
| Positive regulation of RNA metabolic process | 2.13E-07 |
| GO-MF | |
| Transcription factor binding | 9.34E-11 |
| Transcription from RNA polymerase II promoter | 1.72E-09 |
| RNA polymerase II distal enhancer sequence-specific DNA binding transcription factor activity | 5.64E-09 |
| DNA binding | 6.20E-08 |
| Sequence-specific DNA binding | 8.61E-08 |
| Positive regulation of transcription, DNA-dependent | 1.22E-07 |
| Negative regulation of transcription, DNA-dependent | 6.69E-07 |
| Protein dimerization activity | 7.12E-07 |
| Protein heterodimerization activity | 8.13E-05 |
| Protein kinase binding | 8.30E-05 |
| GO-CC | |
| Nuclear lumen | 1.51E-05 |
| Nucleoplasm | 1.65E-05 |
| Nuclear part | 7.71E-05 |
| Organelle lumen | 8.69E-05 |
| Nucleoplasm part | 9.60E-05 |
| Membrane-enclosed lumen | 9.90E-05 |
| Nucleus | 0.000389 |
| Transcription factor complex | 0.000649 |
| Nuclear matrix | 0.00118 |
| Protein complex | 0.00294 |