Figure 5.

Curcumin alleviates mitochondrial dysfunction and increased ATP production in gastrocnemius of TNBC mice. (a–c) Transmission electron microscope observation of the gastrocnemius in the healthy group, the model group and the curcumin group (green: myofibrils; orange: sarcomere Z-line; blue: H band; reddish-brown: mitochondria; purple: edema; left: 20,000x magnification; right: 50,000x magnification). (d) Statistical analysis of ATP content in gastrocnemius tissue of mice in three groups (n = 4/group). ^∗p < 0.05 and ^∗∗∗∗p < 0.0001 by t-test, compared to the model group. Data were shown as mean ± standard errors of the mean.