Table 3.

Multivariable-Adjusted Associations of Adipose Tissue Phenotypes with Incident CVD in DHS and UKB

	Incident CVD - DHS (N=1,731)			Incident CVD - UKB (N=22,354)
	N	HR (95% CI)	p-value	N	HR (95% CI)	p-value
Model 1
High VAT-High LF	609	2.03 (1.28-3.21)	.002	7848	1.59 (1.35-1.87)	<.001
High VAT-Low LF	257	2.42 (1.41-4.13)	.001	2822	2.00 (1.65-2.43)	<.001
Low VAT-High LF	257	1.21 (0.63-2.31)	.55	2982	1.40 (1.12-1.75)	.003
Model 2
High VAT-High LF	609	1.20 (0.70 – 2.06)	.50	7848	1.10 (0.90-1.34)	.34
High VAT-Low LF	257	1.53 (0.86 – 2.71)	.15	2822	1.50 (1.22-1.85)	<.001
Low VAT-High LF	257	1.04 (0.54 – 1.99)	.91	2982	1.24 (0.99-1.55)	.06

Hazard ratios (HR) calculated for incident CVD using Cox proportional-hazards model. Referent group is low VAT-low LF (DHS N = 608; UKB N = 8702)

Model 1 is unadjusted

Model 2 is adjusted for age and BMI