TABLE 2.

Depression, Alcohol, and Cannabis Use from Baseline to End of Treatment

		Baseline	Week 4	Week 9	Week 14
		n = 85	n = 85	n = 70	n = 72
Group						Significant Effects
		Mean (SD)/%	Mean (SD)/%	Mean (SD)/%	Mean (SD)/%
Depression	EDR	47.26 (6.59)	28.31 (4.48)	28.48 (7.01)	29.36 (9.97)	LT, QT, G, G x LT, G x QT
(CDRS-R)	CBTD	49.84 (7.66)	44.12 (8.99)	41.10 (11.14)	37.85 (12.98)
	ETAU	45.04 (6.07)	38.40 (6.28)	35.87 (9.32)	32.26 (8.99)
Alcohol	EDR	2.71 (2.55)	1.09 (2.05)	1.15 (1.76)	1.07 (1.86)	LT, QT
Use	CBTD	2.75 (2.21)	2.36 (2.43)	1.86 (2.41)	1.75 (2.05)
(ACQ)	ETAU	2.36 (2.31)	1.80 (2.18)	1.48 (2.02)	1.30 (2.14)
Heavy	EDR	1.97 (2.62)	0.74 (1.82)	0.62 (1.33)	0.46 (1.32)	LT
Alcohol Use	CBTD	2.17 (2.04)	1.44 (2.47)	1.67 (2.27)	1.10 (2.02)
(ACQ)	ETAU	1.88 (2.40)	1.24 (1.79)	1.26 (1.94)	0.78 (1.88)
% Days of	EDR	37.08 (31.53)	22.46 (24.94)	18.17 (27.82)	16.71 (25.15)	LT, QT, G, G x LT, G x QT
Cannabis Use	CBTD	56.62 (35.67)	47.36 (39.95)	37.57 (35.03)	27.89 (29.78)
(DC)	ETAU	58.27 (31.26)	31.78 (29.46)	22.81 (29.93)	25.52 (29.27)
% Cannabis	EDR	31.43	51.43	57.69	53.57	LT
Negative	CBTD	24.00	33.33	33.33	45.00
Drug Screens	ETAU	8.00	28.00	26.09	34.78

Note: n = 85 adolescents who were either early depression responders, or non-early responders randomized to cognitive behavior therapy for depression or enhanced treatment as usual. All groups continued to receive motivation enhancement therapy/cognitive behavior therapy for substance abuse through week 14. ACQ = Alcohol Consumption Questionnaire; CBT-D = cognitive behavior therapy for depression; CDRS-R = Children’s Depression Rating Scale-Revised; DC = Drug Checklist; EDR = Early depression responders; ETAU = enhanced treatment as usual; G = group; LT = linear time; QT = quadratic time.