. Author manuscript; available in PMC: 2022 Feb 6.
Published in final edited form as: Metab Eng. 2021 Nov 25;69:175–187. doi: 10.1016/j.ymben.2021.11.006
This is an open access article under the CC BY-NC-ND license (http://creativecommons.org/licenses/by-nc-nd/4.0/).