APPENDIX E.

FEMORAL-POPLITEAL DVT SUBGROUP: CONTINUOUS TRIAL OUTCOMES, ANY ANGIOJET-PCDT VERSUS CONTROL

Outcome	Control* (n = 91)		PCDT (n = 78)		PCDT: control difference
	n	Mean (SE)	n	Mean (SE)	Mean difference (SE)	P value
Villalta scale score
At 6 mo	76	3.63 (0.53)	69	2.96 (0.56)	−0.67 (0.58)	.25
At 12 mo	67	3.71 (0.51)	65	3.09 (0.53)	−0.62 (0.53)	.24
At 18 mo	54	3.79 (0.54)	56	3.22 (0.55)	−0.57 (0.58)	.32
At 24 mo	57	3.88 (0.61)	62	3.35 (0.63)	−0.53 (0.71)	.46
VCSS score
At 6 mo	75	2.32 (0.33)	68	1.37 (0.34)	0.95 (0.40)	.02
At 12 mo	66	1.96 (0.35)	62	1.59 (0.36)	0.37 (0.43)	.38
At 18 mo	52	2.22 (0.38)	55	1.56 (0.38)	0.66 (0.46)	.16
At 24 mo	49	2.50 (0.39)	58	1.63 (0.37)	0.87 (0.47)	.06
VEINES-QOL
At 1 mo	82	14.06 (2.68)	78	13.49 (2.75)	−0.57 (3.58)	.87
At 6 mo	76	25.49 (2.53)	68	26.47 (2.62)	0.98 (3.24)	.76
At 12 mo	67	28.12 (2.57)	64	28.27 (2.64)	0.15 (3.24)	.96
At 18 mo	54	27.28 (2.52)	56	28.25 (2.56)	0.97 (3.09)	.76
At 24 mo	55	26.44 (2.73)	61	28.22 (2.77)	1.78 (3.38)	.60
VEINES symptoms
At 1 mo	82	14.86 (2.56)	78	13.79 (2.62)	−1.07 (3.27)	.74
At 6 mo	76	22.68 (2.47)	68	23.91 (2.56)	1.23 (3.14)	.69
At 12 mo	67	22.69 (2.38)	64	23.39 (2.44)	0.70 (2.93)	.81
At 18 mo	54	22.71 (2.48)	56	22.87 (2.51)	0.16 (3.04)	.96
At 24 mo	55	22.72 (2.74)	61	22.35 (2.77)	−0.37 (3.43)	.91

DVT = deep vein thrombosis; PCDT = pharmacomechanical catheter-directed venous thrombolysis; QOL = quality of life; SE = standard error; VCSS = venous clinical severity scale; VEINES = Venous Insufficiency Epidemiologic and Economic Study; VEINES-QOL = Venous Insufficiency Epidemiologic and Economic Study-Quality of Life.

^*Treatment groups are per-protocol patients.