Table 5.
Outcomes of AngioJet-PCDT Versus Control through 30 Days of Follow-Up
| Outcome | Control * (n = 191) |
PCDT (n = 173) |
PCDT – control difference |
|||
|---|---|---|---|---|---|---|
| n | Mean (SE) | n | Mean (SE) | Mean difference (SE) | P value | |
| All patients, any AngioJet method | ||||||
| Change in leg pain severity, to day 10† | 169 | 0.53 (0.20) | 156 | 0.13 (0.26) | −0.40 (0.33) | .22 |
| Change in leg pain severity, to day 30 | 164 | −0.09 (0.21) | 157 | −0.43 (0.28) | −0.34 (0.35) | .34 |
| Change in leg circumference (cm), to day 10 | 170 | −1.25 (0.13) | 165 | −1.61 (0.17) | −0.35 (0.21) | .09 |
| Change in leg circumference (cm), to day 30 | 166 | −1.73 (0.14) | 166 | −2.28 (0.15) | −0.55 (0.21) | .009 |
| CFV diameter (mm), at day 30 | 165 | 2.5 (6.2) | 167 | 1.4 (4.7) | −1.1 (−1.5) | .05 |
| PV diameter (mm), at day 30 | 162 | 5.4 (5.9) | 166 | 3.3 (4.0) | −2.1 (−1.9) | .0002 |
| All patients, AngioJet delivery of rt-PA | ||||||
| Change in leg pain severity, to day 10 | 169 | 0.53 (0.20) | 67 | −0.12 (0.33) | −0.65 (0.39) | .09 |
| Change in leg pain severity, to day 30 | 164 | −0.09 (0.21) | 70 | −0.51 (0.35) | −0.43 (0.41) | .30 |
| Change in leg circumference (cm), to day 10 | 170 | −1.25 (0.13) | 71 | −1.62 (0.26) | −0.37 (0.29) | .21 |
| Change in leg circumference (cm), to day 30 | 166 | −1.73 (0.14) | 72 | −2.35 (0.23) | −0.61 (0.27) | .03 |
| CFV diameter (mm), at day 30 | 165 | 2.5 (6.2) | 71 | 0.8 (2.2) | −1.7 (−4.0) | <.001 |
| PV diameter (mm), at day 30 | 162 | 5.4 (5.9) | 68 | 1.8 (2.9) | −3.6 (−0.4) | <.001 |
| Fem-Pop DVT, any AngioJet method | ||||||
| Change in leg pain severity, to day 10 | 83 | −1.39 (0.17) | 77 | −1.43 (0.27) | −0.04 (0.31) | .89 |
| Change in leg pain severity, to day 30 | 82 | −1.84 (0.19) | 77 | −2.06 (0.22) | −0.22 (0.29) | .43 |
| Change in leg circumference (cm), to day 10 | 82 | 0.79 (0.29) | 73 | 0.73 (0.41) | −0.07 (0.50) | .89 |
| Change in leg circumference (cm), to day 30 | 81 | −0.07 (0.29) | 72 | 0.13 (0.45) | 0.20 (0.53) | .71 |
| Iliofemoral DVT, any AngioJet method | ||||||
| Change in leg pain severity, to day 10 | 87 | −1.13 (0.19) | 67 | −1.76 (0.22) | −0.63 (0.29) | .03 |
| Change in leg pain severity, to day 30 | 84 | −1.63 (0.21) | 70 | −2.47 (0.22) | −0.84 (0.30) | .006 |
| Change in leg circumference (cm), to day 10 | 87 | −0.29 (0.28) | 71 | −0.40 (0.32) | −0.68 (0.43) | .11 |
| Change in leg circumference (cm), to day 30 | 83 | −0.10 (0.32) | 72 | −0.89 (0.35) | −0.80 (0.47) | .09 |
CFV = common femoral vein; DVT = deep vein thrombosis; Fem-Pop, femoral-popliteal; PCDT = pharmacomechanical catheter-directed venous thrombolysis; PV = popliteal vein; rt-PA = recombinant tissue plasminogen activator; SE = standard error.
*
Treatment groups are per-protocol populations.
†
Leg pain severity was assessed as points on a 7-point Likert scale.