Figure 3.
Schematic depicting the circadian control of homeostatic leukocyte trafficking in the lung. The diagram is synthesized from data in several recent publications detailed in this review (107–110). Cell-surface markers important for rhythmic homing of leukocytes are depicted. Receptors whose cell surface expression oscillates in a circadian manner are colored purple. Also depicted are genes important for rhythms in leukocyte removal by interstitial phagocytic cells and for rhythmic homing to area lymph nodes.