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. 2022 Jan 28;74:103322. doi: 10.1016/j.amsu.2022.103322

Fig. 3.

Fig. 3

A and B. Initial diagnosis in 2010. A; There is a sheet-like growth pattern with necrosis (star) and scattered mitotic figures (H&E, X40). B; Ki-67 proliferative index is estimated at 15.0% (X40). C and D; First recurrence in 2016. C; There is clear evidence of brain invasion (H&E, X40), insert; further highlighted with GFAP immunostain (X40), D; Ki-76 proliferative index is estimated at 15.0% (X40). E and F; Second recurrence in 2020. E; There is sheet-like growth, with no evidence of brain invasion (H&E, X40), F; Ki-67 proliferative index is 5.0% (X40).