Fig. 7.

Changes in bile acid profile of HFD-fed mice after Au@P-NPs. (a) Profile of bile acids in plasma. Profile of bile acids in faecal samples. The mRNA was isolated from indicated fat tissues of mice and the expression pattern of indicated genes was measured by RT-PCR. (c) Ileum. (d) Liver. (e) eWAT. (f) iWAT. (g) BAT. (h) Significant correlation between the mRNA expression profiles of BAT and iWAT (dark values indicate significant levels). (i) Free glycerol content in plasma. One-way ANOVA repeated measurements with BPHT. ∗P ​< ​0.05, ∗∗P ​< ​0.01 and ∗∗∗P ​< ​0.001 for CD vs HFD; ^$P ​< ​0.05, ^$$P ​< ​0.01 and ^$$$P ​< ​0.001 for Au@P-NPs vs HFD.