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. 2022 Feb 1;18:101348. doi: 10.1016/j.tranon.2022.101348

Fig. 4.

Fig 4

Flow cytometry analysis of DLD-1 colon cancer cells (A) and HT-29 colon cancer cells (B) after 24 h incubation with PtPz4 (10 μM), PtPz6 (10 μM), cisPt (10 μM), anti-MUC1 (5 μg/mL), PtPz4 + anti-MUC1 (10 μM + 5 μg/mL), PtPz6 + anti-MUC1 (10 μM + 5 μg/mL), and cisPt + anti-MUC1 (10 μM + 5 μg/mL) and successive staining with Annexin V and propidium iodide. The data are presented as mean percentage values from 3 independent experiments (n = 3) done in duplicate. *P < 0.05, **P < 0.01, ***P < 0.001 compared to the untreated control; ##P < 0.01, ###P < 0.001 compared to PtPz4 monotherapy; ΔP < 0.05, ΔΔΔP < 0.001 compared to PtPz6 monotherapy; ††P < 0.01, †††P < 0.001 compared to cisPt monotherapy; ‡P < 0.05, ‡‡P < 0.01, ‡‡‡P < 0.001 compared to anti-MUC1 monotherapy.