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. 2022 Jan 24;15:800313. doi: 10.3389/fncel.2021.800313

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Copyright © 2022 Govorunova, Sineshchekov and Spudich.

This is an open-access article distributed under the terms of the Creative Commons Attribution License (CC BY). The use, distribution or reproduction in other forums is permitted, provided the original author(s) and the copyright owner(s) are credited and that the original publication in this journal is cited, in accordance with accepted academic practice. No use, distribution or reproduction is permitted which does not comply with these terms.

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Crystal structures of CrChR2 (6EID; Volkov et al., 2017) and GtACR1 (6EDQ; Li et al., 2019). The side chains of six glutamates conserved in most CCRs and the chromophore are shown as spheres. The intramolecular tunnel is shown in green. SB⁺, protonated Schiff base.