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. 2021 Dec 8;13(1):169–179. doi: 10.1002/jcsm.12862

Table 4.

Muscle quantity related factors in COVID‐19 patients

Characteristics PMAI ≤median a PMAI >median a P value
Patients (N) 53 60
Age (years) 73 (63–84) 66 (54–78) 0.001 c
Gender (male/female) 33/20 (62.3/37.7%) 36/24 (60.0/40.0%) 0.975 b
Body height (cm) 170 (168–180) 173 (165–180) 0.810 d
Body weight (kg) 80 (67–90) 80 (70–93) 0.041 c
BMI (kg/m2) 26.1 (23.0–27.8) 26.8 (23.9–30.6) 0.024 c
BMI (>30 kg/m2) 12 (22.6%) 17 (28.3%) 0.137 b
Pre‐existing comorbidities
Arterial hypertension 39 (73.6%) 34 (56.7%) 0.002 b
Cardiovascular disease 35 (52.8%) 26 (43.3%) 0.093 b
Diabetes mellitus 20 (37.7%) 18 (30.0%) 0.162 b
Chronic respiratory disease 12 (22.8%) 11 (18.3%) 0.161 b
Cerebrovascular disease 16 (30.2%) 12 (20.0%) 0.346 b
COVID‐19 severity/outcome 0.088 b
Uncomplicated 19 (35.8%) 25 (41.7%)
Complicated 13 (24.5%) 23 (38.3%) 0.803 b
Critical 21 (39.6%) 12 (20.0%) 0.092 b
Deceased 15 (28.3%) 3 (5.1%) 0.001 b
Medical care
Hospital care 53 (100%) 60 (100%) 1.000 d
Hospital care duration (days) 19 (11–26) 12 (7–21) 0.020C
Intensive care 17 (32.1%) 12 (20.3%) 0.290 b
Intensive care duration (days) 25 (14–47) 13 (8–25) 0.100 c
Invasive ventilation 14 (26.4%) 9 (15.3%) 0.239 b
Ventilation duration (days) 22 (7–39) 11 (5–22) 0.217 d
Vasopressor therapy 11 (21.6%) 7 (11.7%) 0.313 b
Renal replacement therapy 5 (10.0%) 4 (7.9%)
ECMO 3 (5.8%) 0 (0.0%) 0.255 d
No anticoagulation 4 (7.5%) 3 (5.1%)
Prophylaktische LMWH/heparin 29 (54.7%) 40 (66.7%) 0.859 b
Therapeutische LMWH/heparin 20 (37.7%) 17 (28.3%) 0.794 b
Dexamethasone 26 (49.1%) 27 (45.0%) 0.257 b

Patient characteristics are presented as median (interquartile range) or number (%).

a

The gender‐specific median PMAI (male: 246.9 mm2/m2, female: 224.1 mm2/m2) derived from the COVID‐19 Cohort I was applied.

b

χ 2 test.

c

Mann–Whitney U test.

d

Student's t test.