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. 2022 Jan 24;11:790912. doi: 10.3389/fonc.2021.790912

Table 1.

Target substrates for FBXO22 degradation.

Substrate Description Reference
KDM4A Lysine demethylase 4A (3)
KDM4B Lysine demethylase 4B (5)
p53 Tumor protein P53 (4)
P21 (CDKN1A) Cyclin-dependent kinase inhibitor 1A (1)
KLF4 Kruppel-like factor 4 (8)
LKB1 (STK11) Liver kinase B1 (10)
BSG Basigin (Ok blood group) (9)
BACH1 BTB domain and CNC homolog 1 (11)
PTEN Phosphatase and tensin homolog (12)
SNAI1 Snail family transcriptional repressor 1 (7)
HDM2 MDM2 proto-oncogene (6)
BAG3 BAG cochaperone 3 (13)
PHLPP1 PH domain and leucine-rich repeat protein phosphatase 1 (14)