Table 3.
Sample Type | Test | Sensitivity (P-value) | Specificity (P-value) | PPV (P-value) | NPV (P-value) | AUC (P-value) |
---|---|---|---|---|---|---|
Overall | Pathology vs Molecular test | < 0.001 | 0.314 | 0.379 | < 0.001 | < 0.001 |
Pathology vs Parallel test | 0.016 | 1.000 | 0.977 | 0.034 | 0.188 | |
Molecular test vs Parallel test | < 0.001 | 0.314 | 0.389 | < 0.001 | < 0.001 | |
Tissue | Pathology vs Molecular test | < 0.001 | 1.000 | 1.000 | 0.001 | < 0.001 |
Pathology vs Parallel test | 1.000 | 1.000 | 1.000 | 1.000 | 1.000 | |
Molecular test vs Parallel test | < 0.001 | 1.000 | 1.000 | 0.001 | < 0.001 | |
CNB | Pathology vs Molecular test | < 0.001 | 0.313 | 0.366 | 0.005 | 0.053 |
Pathology vs Parallel test | 0.003 | 1.000 | 0.965 | 0.009 | 0.199 | |
Molecular test vs Parallel test | < 0.001 | 0.313 | 0.381 | < 0.001 | 0.003 |
Abbreviations: PPV, positive predictive value; NPV, negative predictive value; AUC, area under the curve; CNB, core needle biopsy.