Table 3.

Juvenile spondyloarthritis flare (JSpAflare) core measures and frequency of flare visits where each core met the clinically meaningful change from index visit.

Core measures	Clinically meaningful (absolute) change from reference/ index visit	Frequency meeting flare criteria N (%)
		Development Cohort	Validation Cohort
1. Caregiver/patient assessment of overall well-being	≥2	12 (75.0)	4 (80.0)
2. Physician assessment of disease activity	≥2	13 (81.3)	5 (83.3)
3. Caregiver/patient assessment of pain	≥2	14 (87.5)	3 (50.0)
4. Function: PROMIS mobility or upper extremity function or CHAQ	PROMIS: ≥3 CHAQ: ≥0.125	8 (80.0)	2 (40.0)
5. Active joint count	≥1	12 (75.0)	6 (100.0)

Legend. Flare defined as clinically meaningful worsening in absolute values of ≥3 core measures from the reference visit. PROMIS = Patient Reported Outcomes Measurement Information System; CHAQ = Child Health Assessment Questionnaire.