TABLE 2.

Main adjusted models ^a for estimating the odds of hospitalization and pneumonia by severity predictors

Model parameter	Hospitalization			Pneumonia
	Odds ratio b	95% CI	P value	Odds ratio b	95% CI	P value
Demographics
Age (per year)	1.04	1.03, 1.05	<0.001	1.02	1.01, 1.03	<0.001
Female vs. male	0.62	0.47, 0.80	<0.001	1.03	0.65, 1.64	0.907
Race/ethnicity
Black vs. White	0.51	0.22, 1.22	0.131	0.73	0.57, 0.93	0.011
Asian vs. White	0.15	0.07, 0.32	<0.001	3.22	2.59, 3.99	<0.001
Other vs. White	0.86	0.42, 1.73	0.666	2.44	1.53, 3.90	<0.001
Hispanic/Latino vs. non‐Hispanic/Latino	0.49	0.31, 0.78	0.003	0.24	0.03, 1.76	0.159
Coinfection
Influenza vs. influenza + coinfection	2.99	1.14, 7.85	0.026	2.27	1.25, 4.09	0.007
Disease severity indicators
Underlying health conditions	2.18	1.65, 2.89	<0.001	3.21	1.76, 5.83	<0.001
NEWS	1.49	1.37, 1.62	<0.001	6.10	3.60, 10.32	<0.001

Abbreviations: 95% CI, 95% confidence interval; NEWS, National Early Warning Score for acutely ill patients.

^a Main models were adjusted for all variables in table.

^b Model estimates for odds ratios and 95 CI were based on multivariable logistic regressions using robust variance estimates ²⁷ adjusted for clustering by study site.