Table 1.
Clinical and histological information on patients.
| Normal skin a | ||||
|---|---|---|---|---|
| Average age (year) | 46 | |||
| Men/women | 1/4 | |||
| Common nevi | ||||
| Average age (year) | 37 | |||
| Men/women | 4/6 | |||
| Dysplastic nevi b | ||||
| Average age (year) | 56 | |||
| Men/women | 2/8 | |||
| Melanomas | ||||
| Average age (year) | 64 | |||
| Men/women | 4/6 | |||
| Subclassification | (n=4) | (n=2) | (n=2) | (n=2 |
| AJCC stage | IIA | IB | IIB | IIIC |
| Breslow Depth | T3a (2-3mm) | T2a (2 mm) | T3b (4 mm) | T4a (5 mm) |
| Clark level | IV | IV | IV | IV |
| Ulceration | absent | absent | present (1/2) | absent |
| Growth Phase | vertical | radial and vertical | vertical | radial and vertical |
| Mitoses/mm2 | 2-3 | 4-5 | 18-20 | 8-9 |
| Tumoral lymphocytic infiltration | present (2/4) | present | absent | present |
| Peritumoral lymphocytic infiltration | present | present | present | present |
| Vascular invasion | absent | present | absent | absent |
| Overall | 35 |
a
All normal skin sections were from patients who underwent surgery for suspect breast cancer.
b
All dysplastic nevi showed severe atypia but negative margins. AJCC, American Joint Committee on Cancer.