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. 2022 Jan 24;13:803338. doi: 10.3389/fphar.2022.803338

TABLE 1.

Main coumarins and their vegetal sources.

Plant species Coumarins References
Apiaceae/Umbelliferae
 Anethum graveolens (L.) Esculetin, scopoletin, furanocoumarin, oxypeucedanin, oxypeucedanin hydrate, falcarindiol Kovač-Bešović and Durić, (2003); Kaur and Arora, (2010)
(Dill)
 Angelica archangelica (L.) Angelicin, osthole, bergapten, imperatorin, isoimperatorin, oreoselone, oxypeucedanin, psoralen, umbelliferone, xanthotoxin, xanthotoxol, umbelliprenin Kumar et al., 2013; Forycka and Buchwald, (2019)
(Angelica)
 Apium graveolens (L.) Esculetin, bergapten, celerin, celereoside, isoimperatorin, isopimpinellin, osthenol, seselin, scopoletin, psoralen, umbelliferone, xanthotoxin Garg et al., 1979; Najda et al., 2015; Arsenov et al., 2021
(Celery)
 Coriandrum sativum (L.) (Coriander) Coumarin 7-substituted derivatives Sharifi-Rad et al. (2021)
 Cuminum cyminum (L.) (Cumin) Coumarin Rebey et al. (2012)
 Daucus carota (L.) Bergapten, isopimpinellin, umbelliferone, xanthotoxin Ozçelik and Kusmenoglu, (2004); Kenari et al., 2021
(Carrot)
 Foeniculum vulgare Mill. (Fennel) Scopoletin, bergapten, imperatorin, 8-methoxypsoralen, psoralen Kaur and Arora, (2010); Yang et al., 2015
 Pastinaca sativa (L.) Angelicin, bergapten, isopimpinellin, oxypeucedanin hydrate, xanthotoxin, imperatorin, psoralen Kenari et al. (2021)
(Parsnip)
 Petroselinum crispum (Mill.) Fuss Bergapten, oxypeucedanin, 8-metoxypsoralen, imperatorin, isoimperatorin, isopimpinellin, psoralen Manderfeld et al., 1997; Arsenov et al., 2021
(Parsley)
 Pimpinella anisum (L.) (Aniseed) Bergapten, scopoletin, umbelliferone, umbelliprenine Sun et al. (2019)
Rutaceae
 Aegle marmelos (L.) Corrêa Angelicin, umbelliferone, scopoletin, marmesinin, 8-hydroxypsoralen, marmelosin Avula et al. (2016)
(Bael fruit)
 Citrus x aurantiifolia (Christm.) Swingle Bergamottin, 5-geranyloxy-7-Methoxycoumarin, imperatorin, isoimperatorin, isopimpinellin, limettin, marmesin, oxypeucedanin hydrate, phellopterin, scoparone Dugrand et al., 2013; Dugrand-Judek et al., 2015
(Lime)
 Citrus x limon (L.) Osbeck Limettin, 5-geranyloxy-7-methoxycoumarin, oxypeucedanin hydrate, byakangelicol, oxypeucedanin, 8-geranyloxypsoralen, bergamottin, umbelliferone, heraclenin, phellopterin, osthole, auraptene, isopimpinellin, bergapten Dugrand et al., 2013; Dugrand-Judek et al., 2015
(Lemon)
 Citrus x sinensis (L.) Osbeck Herniarin, scopoletin, scoparone, umbelliferone, xanthyletin, bergaptol Dugrand et al., 2013; Dugrand-Judek et al., 2015
(Sweet orange)
 Citrus x paradisi Macfad. (Grapefruit) Bergamottin, auraptene, limettin, scopolin, bergapten, bergaptol, isopimpinellin, osthole Dugrand et al., 2013; Dugrand-Judek et al., 2015
Asteraceae/Compositae
 Arnica montana (L.) (Arnica) Scopoletin, umbelliferone Kriplani et al. (2017)
 Chamaemelum nobile (L.) All Scopolin (7-β-d-glucopyranosyl-scopoletin), umbelliferone, herniarin, scopoletin European Medicines Agency, (2011)
(Roman Chamomile)
 Cichorium intybus (L.) (Chicory) Umbelliferon, esculetin (6,7-dihydrocumarin) scopoletin, esculetin and cichorin Das et al., 2016; Aisa et al., 2020
 Matricaria chamomilla (L.) Umbelliferone, herniarin, skimmin, daphin, daphnetin Petruľová-Poracká et al. (2013)
(Chamomille)
 Fabaceae/Leguminosae
  Dipteryx odorata (Aubl.) Forsyth f Esculin, esculetin Oliveros-Bastidas et al. (2013)
 (Tonka Bean)
  Glycyrriza glabra (L.) (Liquorice) Glycycoumarin, isoglycycoumarin, licopyranocoumarin, isotrifoliol, glycyrol, glycyrurol, licoarylcoumarin, glycyrin Zang, (2020)
  Trigonella foenum-graecum (L.) (Fenugreek) Hymecromone, trigocoumarin, trigoforin, scopoletin Dini and Laneri, (2021)
 Moraceae
  Oleae europaea (L.) Esculetin, scopoletin, esculin Hashmi et al., 2015; European Medicines Agency, (2017)
 (Olive)
  Ficus carica (L.) Umbelliferone, psoralen, bergapten Ammar et al. (2015)
(Fig)
 Araliaceae
  Eleutherococcus senticosus (Rupr. & Maxim.) Maxim Isofraxidin Guo et al. (2019)
(Siberian Ginseng)
 Lamiaceae/Labiadae
  Ocimum basilicum (L.) Esculetin, esculin, coumarin, ocimarin Zahran et al. (2020)
(Basil)
 Lauraceae
  Cinnamomum sp. (Cinnamon) Coumarin, scopoletin Wang et al., 2013; Ananthakrishnan et al., 2018
C. zeylanicum has a low content compared with other species
  Persea americana Mill. (Avocado) Scopoletin Bhuyan et al. (2019)
 Tiliaceae
  Tilia cordata Mill. (Linden) Scopoletin Arcos et al. (2006)
 Urticaceae
  Urtica dioica (L.) Umbelliferone, esculetin, scopoletin Esposito et al., 2019; Repajić et al., 2021
(Nettle)