Table 3.
Effects of simvastatin on morphometric parameters.
|
Groups |
Parameters |
|||
|---|---|---|---|---|
| Body weight (g) | Body mass index (g/cm2) | Adiposity index (g/mm tibial length) |
Liver index (g/mm tibial length) | |
| NCD fed | 240 ± 0.02∗∗∗ | 0.66 ± 0.12∗∗∗ | 0.178 ± 0.42∗∗∗ | 0.272 ± 0.24∗∗∗ |
| HFD fed | 450 ± 0.78∗∗∗ | 1.24 ± 0.19∗∗∗ | 0.438 ± 0.65∗∗∗ | 0.472 ± 0.21∗∗∗ |
| Simvastatin (10 mg/kg) | 290 ± 0.56∗∗∗ | 0.80 ± 0.45∗∗∗ | 0.283 ± 0.76∗∗∗ | 0.338 ± 0.89∗∗∗ |
| Simvastatin (20 mg/kg) | 240 ± 0.38∗∗∗ | 0.66 ± 0.76∗∗∗ | 0.182 ± 0.19∗∗∗ | 0.267 ± 0.01∗∗∗ |
Values are mean ± s. d; ∗∗∗p < 0.001, ∗∗p < 0.01, ∗p < 0.1.