Figure 1.
Results of the mRNA expression analysis of 770 genes using the nCounter® PanCancer Immune Profiling Panel.
nCounter analysis was successfully carried out on tumor samples from 56 resected PDAC patients (27 patients from the M1-PUL and 29 patients from the M1-ANY cohort). (A) Heatmap of mRNA expression with automated clustering according to M1-PUL versus M1-ANY cohorts. (B) Differentially expressed genes depicted as a volcano plot. (C) Networks of gene products form the top 20 differentially expressed genes visualized by using the STRING database.
Adj., adjusted; M1-PUL, pulmonary metastasis; M1-ANY, any metastases excluding lung-only involvement; mRNA, messenger RNA; PDAC, pancreatic ductal adenocarcinoma.