Fig. 2.

Effect of GSK2606414 on ER stress markers. (a) Immunofluorescence staining of N2A cells, representing co-expression of PDI & GRP78. Photographs were taken at 400× magnification (scale: 25 ​μM) (b) Representative immunoblots of ER stress markers. Values are expressed as mean ​± ​SEM (n ​= ​3). NC: normal N2A cells, GSK 1: normal N2A cells treated with GSK260414 (1 ​μM), HG: hyperglycemic N2A cells (30 ​mM β-D glucose), HG+ ​GSK 0.5: HG cells treated with GSK260414 (0.5 ​μM), HG+ ​GSK1: HG cells treated with GSK260414 (1 ​μM). ^^^P ​< ​0.001 v/s NC and ∗∗P ​< ​0.01, ∗∗∗P ​< ​0.001 v/s HG.