Fig. 5.

Effect of GSK2606414 on apoptosis. (a) Immunofluorescence staining of CHOP (red) (b) Representative immunoblots of proteins involved in apoptosis. Photographs were taken at 400× magnification (scale: 10 ​μM). Values are expressed as mean ​± ​SEM (n ​= ​3). NC: normal N2A cells, GSK 1: normal N2A cells treated with GSK260414 (1 ​μM), HG: hyperglycemic N2A cells (30 ​mM β-D glucose), HG+ ​GSK 0.5: HG cells treated with GSK260414 (0.5 ​μM), HG+ ​GSK1: HG cells treated with GSK260414 (1 ​μM). ^^^P ​< ​0.001 v/s NC and ∗∗∗P ​< ​0.001 v/s HG. (For interpretation of the references to color in this figure legend, the reader is referred to the Web version of this article.)